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Katherine A de Villiers Selected Research

hemozoin

1/2021Heme Detoxification in the Malaria Parasite: A Target for Antimalarial Drug Development.
11/2018Hemozoin inhibiting 2-phenylbenzimidazoles active against malaria parasites.
12/2015Design, Synthesis, and Evaluation of Novel Ferroquine and Phenylequine Analogues as Potential Antiplasmodial Agents.
10/2015Alkoxide coordination of iron(III) protoporphyrin IX by antimalarial quinoline methanols: a key interaction observed in the solid-state and solution.
2/2010Crystallization of synthetic haemozoin (beta-haematin) nucleated at the surface of lipid particles.
8/2009Recent advances in the discovery of haem-targeting drugs for malaria and schistosomiasis.
9/2006Haemozoin (beta-haematin) biomineralization occurs by self-assembly near the lipid/water interface.

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Katherine A de Villiers Research Topics

Disease

8Malaria
01/2021 - 09/2006
1Schistosomiasis (Bilharziasis)
08/2009

Drug/Important Bio-Agent (IBA)

7hemozoinIBA
01/2021 - 09/2006
3Heme (Haem)IBA
01/2021 - 09/2006
2Antimalarials (Antimalarial Agents)IBA
01/2021 - 12/2015
2Pharmaceutical PreparationsIBA
01/2021 - 10/2015
1Coordination ComplexesIBA
10/2015
1protoporphyrin IXIBA
10/2015
1LipidsIBA
02/2010
1Hemin (Panhematin)FDA Link
09/2006

Therapy/Procedure

1Synchrotrons
04/2009